Molecular genetics of human visual pigments.

INTRODUCTION .......................................... 403 COLOR VISION .......................................... 405 RED AND GREEN PIGMENTS ................................. 406 Psychophysics of Red~Green Color Blindness ....................... 406 Molecular Genetics of RedIGreen Color Blindness .................... 407 Variation in Normal Color Vision .............................. 409 Blue Cone Monochromacy .................................. 412 THE BLUE PIGMENT ....................................... 415 Psychophysics of Tritanopia .................................. 415 Molecular Genetics of Tritanopia .............................. 415 RHODOPSIN ............................................. 416 Inherited Defects in Rod Vision ............................... 416 Rhodopsin Mutations in Retinitis Pigmentosa ....................... 417 Biochemical Characteristics of Mutant Rhodopsins .................... 418 PERSPECTIVE ........................................... 420